Personal Area Registration Form
Personal Area Registration Form
17-19 December 2023
FF-UL, Lisboa
17-19 December 2023
FF-UL, Lisboa

Short Course

16th December 2023

Thematic short courses have been provided since the first “Encontro Nacional de Cromatografia” (ENC) and the 13th meeting will continue this long-standing tradition. 

This year the short course will focus on the exploration of drug metabolites of a new emerging drug of abuse in biological samples, analysed by ultra-high performance liquid chromatography coupled to tandem mass spectrometry (UHPLC-MS/MS). A summary is presented below.

Registration is mandatory.Please make your registration at your personal area ("booking" menu). If you require further assistance, please contact Andreia Bento da Silva (abentosilva@ff.ulisboa.pt).

All participants will receive a certificate of participation that will include information about the program and number of hours of the short course.

EXPLORING DRUG METABOLISM: THE ROLE OF LC-MS/MS ANALYSIS

  • Andreia Bento da Silva – Faculdade de Farmácia, Universidade de Lisboa

  • Cristina Almeida – Faculdade de Farmácia, Universidade de Lisboa

  • Noélia Duarte – Faculdade de Farmácia, Universidade de Lisboa

  • Paula Marques – Faculdade de Farmácia, Universidade de Lisboa 

Brief summary

The course will explore the potentialities of UHPLC-MS/MS to gain a better understanding of drug absorption, distribution, metabolism, excretion, and toxicology (ADMET). Participants will work on a case-study aiming to identify the metabolites of a new illicit drug, envisioning the detection of drug consumption in routine drug screening. The course will provide an overview of UHPLC-MS/MS (triple quadrupole) analysis and describe several applications. The participants will have the opportunity to explore the equipment and data treatment in a dedicated software. Several research steps needed to identify drugs and their metabolites will be described: 

(1) Optimization of the conditions for the detection of the parent drug and synthetized metabolites;

(2) Searching for additional predicted metabolites in biological samples;

(3) Quantitation of the drug and main metabolites in biological samples. 

Program

16th December 2023

10h00-11h30: Overview of liquid chromatography coupled to mass spectrometry

11h30-12h30: Overview of drug metabolism and ADMET

12h30-14h00: Lunch break

14h00-14h30: Hands-on (UHPLC-MS/MS) – Structural Analysis Laboratory (LAE)

14h30-18h00: Hands-on (data treatment) – room A3.1

 

Who should attend?

Anyone interested in learning and gaining hands on experience with liquid chromatography tandem mass spectrometry, especially those interested in the development of new methodologies and the study of biological samples.

Maximum of 20 participants.

Fee and Payments

  • 50,00 €

Choose the Short Course fee at your personal area - fees menu - and make the payment to secure your place/attendance.

 

Bank Transfer

Account owner: Sociedade Portuguesa de Química
Bank: Millennium BCP (Lisboa, Pt)
IBAN: PT50 0033 0000 4534 5670 6780 5
BIC/SWIFT: BCOMPTPL
Bank Address: Millennium BCP (Avenida 5 de Outubro 60-68, 1050-059 Lisboa, Portugal)

Credit Card

Payment with credit card will is possible at your personal/registration area.

Proforma Invoice

A pro forma invoice can be download at your personal area but first some details must be filled in.

  • Choose a Fee

  • Add a billing address (Billing and Payment icon/menu)

After filling in and confirming the billing address, an orange button (Proforma Invoice) will appear where you can download the document.